Anxiety, stress, and mood swings are common experiences for many people, and researchers are exploring whether cannabinoids like cannabigerol (CBG) might offer natural, supportive effects. In this study, scientists conducted a double‑blind, placebo‑controlled, crossover field trial—one of the most rigorous types of human research—to test the acute effects of CBG on anxiety, stress, and mood in real‑world conditions. This means participants received both CBG and placebo at different times, and neither the participants nor the researchers knew which was given at any point until after the study.

The findings showed that CBG intake was associated with reductions in self‑reported anxiety and stress compared with placebo. Participants also showed improvements in certain measures of mood after receiving CBG, suggesting that the compound may help support feelings of calm and emotional balance in everyday life. While the effects were measured over short time periods soon after CBG use, the controlled environment and crossover design helped strengthen confidence that these differences were linked to CBG rather than other factors.

Although the study focused on immediate, short‑term effects rather than long‑term outcomes, the results contribute to growing interest in how CBG may support mental wellbeing. The authors note that further research, including larger and longer clinical trials, will be valuable to better understand how CBG influences stress and mood over time and in broader populations.

Source

Acute effects of cannabigerol on anxiety, stress, and mood: a double‑blind, placebo‑controlled, crossover, field trial (2024)
Available through the National Library of Medicine (NIH): https://pmc.ncbi.nlm.nih.gov/articles/PMC11246434/