Researchers are increasingly interested in cannabigerol (CBG), a lesser‑known cannabinoid found in the cannabis plant, because of its potential effects on human biology. This review article summarizes what is currently known about the pharmacological properties (how the body interacts with CBG) and biological effects of CBG and some of its synthetic derivatives. The authors looked at studies conducted in cells, animals, and limited human data to better understand how CBG works, how it is processed in the body, and what potential uses it might have for health and wellness.

The review highlights that CBG interacts with several systems in the body, including the endocannabinoid system, which plays a role in regulating mood, appetite, inflammation, pain, and more. CBG has been shown in laboratory and animal studies to have anti‑inflammatory, neuroprotective, antibacterial, and appetite‑stimulating effects. Some research also suggests CBG may support gastrointestinal health and reduce inflammatory responses in the gut. Because CBG acts on multiple targets, its potential effects are broad, but the review emphasizes that most of the evidence so far comes from early studies rather than large clinical trials.

Overall, the authors conclude that CBG shows promising biological action across several areas of health and warrants further research, especially well‑designed human clinical trials. While many of the findings are preliminary, this summary helps outline the range of systems that CBG may influence and provides a scientific foundation for future investigations into how this cannabinoid might support wellness.

Source

Pharmacological Aspects and Biological Effects of Cannabigerol and Its Synthetic Derivatives
Published in Evidence‑Based Complementary and Alternative Medicine (2022)
Available through the National Library of Medicine (NIH): https://pmc.ncbi.nlm.nih.gov/articles/PMC9666035/